In 2024, Keep America Beautiful launched the Greatest American Cleanup in honor of America's 250th birthday, an initiative to clean up and green up communities nationwide by July 4, 2026. Pick Up Pennsylvania, part of the national movement, has announced that registration is open for 2026.

Pick Up Pennsylvania is a yearlong initiative, but events scheduled from March 1 through May 31 will receive free trash bags, gloves, and safety vests provided by support from the Pennsylvania Department of Environmental Protection and PennDOT while supplies last. Events can include litter cleanups, illegal dump cleanups, community greening and beautification, special collections, and anti-litter education events. Events must be registered at http://www.keeppabeautiful.org to receive free cleanup supplies.

As part of the event, the Pennsylvania Department of Environmental Protection and Pennsylvania Waste Industries Association will sponsor trash disposal free of charge or at a reduced rate for registered program participants at participating landfills from April 1 through April 30, with prior approval.

Individuals and groups can help clean up vacant lots, streets, and riverbanks; plant gardens and trees; or mulch a local playground. To host an event, join an event, or inquire about free supplies and trash disposal, visit http://www.keeppabeautiful.org and choose "Programs" and "Pick Up PA" or contact Michelle Dunn, Pick Up Pennsylvania program coordinator, at 724-836-4121, ext. 113, or mdunn@keeppabeautiful.org.

In 2025, from March through May, more than 53,500 people participated in Pick Up Pennsylvania. More than 3.4 million pounds of trash and recyclables was picked up, and more than 22,500 trees, flowers, and other greens were planted.